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You've seen how deep brain stimulation changes parkinson's patients lives,
but they aren't the only patients benefiting. Mark Barrett isn't throwing
a tantrum he has a rare form of a movement disorder called the dystonia.
It causes painful uncontrollable muscle contractions. Here he is trying to do
something we take for granted, walking.
It was pretty much impossible
That's a
Dystonia comes in many forms it can be focal
involving this one's head or neck or eyes
segmental involving once arm and head for example or generalized involving the
whole body
In Mark's case, he has
primary generalized
dystonia. That's a genetic form.
Treatment
depends on the type of dystonia.
Focal dystonia can often be managed with injections of botswana tops
that's harder to do in patients who have
segmental or generalized dystonia
such as Mark has. Mark was on fifty-eight
pills a day to control is movements
It didn't work.
I had to have help constantly.
Someone always had to help me do simple things of brushing my teeth
or
taking a shower or anything.
and all the pills that I took made me sleep all the time, so I basically wore diapers
and didn't get up to eat or anything. I didn't really want to live very much anymore.
because I didn't think it'd ever go away or that I 'd ever be able to live a normal life. Mark's only hope,
DBS, his last treatment option
at age thirteen he would be Vanderbilt's first pediatric patient to ever receive
it. Could neurosurgeons find the targets causing his violent muscle
contractions?
here's Mark walking down the hall weeks after surgery. Unreal,
I didn't think I'd ever be able to
walk down the hall again.
Mark's completely off all medications thanks to DBS, something common for
dystonia patients after surgery So no more debilitating drug side effects
like sleepiness
marks grateful he can now focus on his future doing things normal
tees do.
I work two part time job delivering pizza and going to college at Davenport
University.
I get to talk to people and
socialize
Do my homework and
when i get that good grade then it makes me happy.
DBS can also help patients with another movement disorder called
essential tremor. It affects about five million Americans making it more common
than parkinson's disease. Essential tremor
is an action tremor, it's a tremor of the hands
voice or head
At complete rest, the tremor is gone
but then you try to use your hands
that's when the tremor is activated. You can imagine that would interfere with activities
such as drinking from a glass, eating soup with a spoon,
handwriting. If the tremor is interfering with daily activities and significantly with daily activities and
is not controlled with medication
or the medications are causing intolerable side-effects
then one should consider being evaluated for deep brain stimulation
and like in dystonia, essential tremor patients may also come off all
medications after DBS
So if DBS can help patients with movement disorders, what about patients
with psychiatric disorders? Vanderbilt neurosurgeon doctor Joseph Neimat was
involved in Canadian studies looking at DBS as a treatment for depression
when traditional medications were no longer affective. The sixty percent of
those patients had a response where they're symptoms decreased
substantially more than fifty percent of what they'd had before
and if you speak to those patients, most of them had real benefits. They went back benefit. Most of those precious went back
to work, resumed their normal life. One person, I think, started
her own business, so ,you know, for some of these patients, it was very exciting
and we're still hoping to understand what works in some patients and not others. Doctor
Neimat hopes to answer that question and many more involving TBS and how it may
help patients with the everything from depression obsessive-compulsive disorder
to Tourette syndrome
In the near future,
Vanderbilt will start studies and be only one other handful of centers around
the world doing this type of leading-edge research. We're very excited
that
we're moving into that phase
in the last half hour you've seen how the lives of patients with parkinson's disease
and other movement disorders are being improved
patients are not only regaining their lives but their dignity through treatments like
deep brain stimulation at vanderbilt for more information on Vanderbilt studies
call (615) 936- 8225 or visit Vanderbiltdbs.com
I'm sylvia CastaƱeda. We'll see you next time.