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Thiazolidinediones (better known as glitazones or TZDs) is a class of medications that are
commonly used to treat diabetes. Glitazones work by increasing the sensitivity of certain
muscle and fat cells to insulin which stimulates removal of fatty acids and blood sugar from
the blood. Glitazones share a few common side effects, including swelling, fluid retention,
headhache, and weight gain. These effects are usually mild. Some examples of glitazones
include rosiglitazone (the generic name for Avandia) and pioglitazone (the generic name
for Actos). Talk to your doctor or pharmacist before taking a glitazone as this class of
medications has been linked to an increase risk in heart disease, bladder cancer, and
liver problems. It is always a good idea to ask questions about your medication if you
are unsure or if you experience something out of the ordinary. Use these medications
only as prescribed. To keep up to date with medication information, sign up for RxWiki
Notify.
